Amgen Senior Manager Economic Modeling in Uxbridge, United Kingdom

Senior Economic Modelling Manager

The company:

Amgen is one of the world's largest independent biotechnology companies, with global revenue of $23 billion and nearly 20,000 employees globally. For more than 35 years, Amgen has pioneered biotechnology breakthroughs, to bring state-of-the-art medicines from laboratory to the patient. Amgen has not only discovered and developed innovative human therapeutics, but has invested in cutting edge manufacturing capability and support services to deliver these exciting therapies to medical teams around the world.

The Team:

The Global Economic Modelling Centre of Excellence work in international cross-functional teams developing and supporting product value strategy focusing on evidence-based economic modelling throughout the product life-cycle. The activities of the Global Economic Modelling Centre of Excellence include early modelling for strategic input to development, design and pricing, core models and local model adaptations for Health Technology Assessment (HTA) and price and reimbursement submissions, as well as tools supporting field-based key account value communication.

The Role:

The successful candidate will be the economic modelling COE product lead for Amgen oncology products. The successful candidate will be responsible for designing and executing the economic modelling activities involved in the global launch of new products/indications and in the products life cycle management. The successful candidate will lead the development of the core and the local adaptations of cost-effectiveness and budget impact models in collaboration with cross-functional local and global teams.

Key Responsibilities include:

  • Lead core cost-effectiveness and budget impact model development.

  • Lead local model adaptations to address local requirements, being responsible for the project management, content and execution.

  • Manage a team of junior economic modellers.

  • Effective communication to HTA and reimbursement authorities

  • Interpretation of clinical studies results.

  • Plan and perform additional statistical analyses needed for local adaptations.

  • Input into the design and interpretation of global/local evidence generation activities/studies.

  • Critically review and select relevant model inputs.

  • Generate base case and sensitivity/scenario results.

  • Discuss, re-analyze and present model results.

  • Report the economic section of HTA pricing and reimbursement submissions.

Basis Requirements:

  • MSc in Health Economics with a background in economics or in a quantitative field (such as (bio)statistics, epidemiology or engineering).

  • Extensive working experience in the pharmaceutical industry consultancy, academia, reimbursement agencies or equivalent.

  • Strong experience in development of core and local adaptation of cost-effectiveness, budget impact models.

  • Strong statistical skills, in particular deep knowledge of advanced survival analyses and indirect treatment comparisons

  • Strong Excel programming skills.

  • Strong analytical and communication skills.

  • Strong project management skills.

  • Fluency in English

Preferred Requirements:

  • PhD in Health Economics with a background in economics or in a quantitative field (such as (bio)statistics, epidemiology or engineering).

  • Experience using Visual Basic, TreeAge Pro, R, SAS, STATA, WinBUGS and other software for statistical analyses.

  • Previous experience in oncology

Location: Uxbridge

Remuneration: Competitive salary & comprehensive benefits package including bonus scheme

Amgen is an equal opportunity employer