Amgen Scientist--Cell Line Development in Thousand Oaks, California
In our mission to serve patients, speed is absolutely critical. We're rapidly expanding our hiring initiatives and are excited to unite with the most passionate and brilliant scientific minds who want to join our team - working toward our mission of advancing high potential programs for cancer patients around the world.
Amgen is seeking a Scientist to join the Cell Line Development group in our state-of-the-art research facility at the Amgen headquarters campus located in Thousand Oaks, CA. The Cell Line Development group is responsible for developing production cell lines for Amgen's large molecule pipeline. In this role, the candidate will be responsible for supporting pipeline program advancement and contributing to cell line technology improvements. The candidate will be responsible for the generation and creation of expression vectors and strategies, executing mammalian cell culture processes and optimizing expression as well as utilize solid problem-solving skills to deliver pipeline programs. Additional responsibilities may also include developing innovative methods to support and improve expression technologies, generating relevant data toward publications, patent applications, and regulatory submissions. The candidate will work in a team environment, collaborating with various colleagues in process development, discovery, as well as interact with regulatory and quality experts in support of global regulatory filings.
Doctorate degree or Doctorate degree completed by December 2018
Master's degree and 4 years of Scientific or Bioprocess Development experience
Bachelor's degree and 6 years of Scientific or Bioprocess Development experience
PhD with 2+ years of experience or MS with 8+ years of experience or BS with 10+ years of relevant industrial experience
Previous hands on experience in cell culture with a focus on mammalian cell recombinant protein production
Strong expertise with DNA cloning, expression vector construction and design with proven experience and advanced molecular biology techniques is highly desired
Strong scientific understanding of recombinant protein expression, cell line and gene editing technologies
Understanding of cellular metabolism, media optimization
Our culture is what makes Amgen a special place to work. We have a powerful shared purpose around our mission - to serve patients. We respect one another, recognize contributions, and have embedded collaboration, trust, empowerment and inclusion in all that we do.
Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.