Amgen Principal IS Software Engineer in Thousand Oaks, California

Principal IS Software Engineer

Amgen is seeking a Principal IS Software Engineer and architect to join the multi-site Research & Development Informatics organization at its Thousand Oaks campus. The IS architect/Software Engineer will report to the Executive Director, Research Informatics.

The Research Informatics team supports Discovery Research and Translational Research organizations globally with innovative IS solutions to accelerate and grow Amgen's pipeline of biopharmaceuticals. Our success in informatics is driven by our commitment to the IS Vision to Accelerate Growth through Technology and Informatics. Our success in informatics is driven by our commitment to our patients, to our business clients, and to leveraging superlative technologies that deliver critical business value. We are at an exhilarating moment in the history of biotechnology, with a growing number of opportunities to address serious illness in important new ways. Our approach to research and development focuses on innovative medicines to address unmet medical needs in patients with serious illnesses. We employ state-of-the-art science to drive internal innovation. Our IS strategy is to leverage native AWS cloud capabilities drive speed to value and innovate to meet dynamic business needs.


  • Provide hand-on leadership to our software engineers to design and develop solutions on AWS

  • Lead delivery of technical solutions for portfolio of projects

  • Develop technology strategy, architecture, and roadmap for data and analytics solutions within Research

  • Represent Research IS in the enterprise architecture board

  • Collaborates with internal and external teams to leverage cloud/big data platforms

  • Keeps track of industry and cutting-edge technology trends, connect and foster external networking opportunities to look for new and innovative ways to do business differently

  • Manages the DevOps activities across internal teams and vendor teams to provide guidance, oversight and execution for the entire portfolio

  • Mentors junior software and data engineers on best practices

  • Help instill agile product mindset for our delivery teams

Basic Qualifications

Doctorate degree and 2 years of Information Systems experience


Master's degree and 6 years of Information Systems experience


Bachelor's degree and 8 years of Information Systems experience


Associate's degree and 10 years of Information Systems experience


High school diploma / GED and 12 years of Information Systems experience

Preferred Qualifications:

  • Master's Degree in Computer Science/Engineering/Life sciences

  • 10+ years of experience in agile software design & development working across teams and locations in a biopharma industry

  • Strong written and oral communication skills and technical expertise to be able to communicate effectively with business executives and technology partners.

  • Strong delivery mindset with ability to design and develop large and complex solutions

  • Deep expertise in developing applications in the native AWS environment including but not limited to container technologies (e.g. Docker) and developing microservices

  • Experience in Java, .NET, Python, R, and/or Ruby expertise

  • Expertise in developing web applications and frameworks (e.g. Node.js)

  • Relevant experience in Enterprise Software Architecture, including data architecture and modeling using relational databases running SQL (AWS RDS Oracle) and non-SQL stores (e.g.,S3, graph databases, RDF store)

  • Service Oriented Architecture (REST/JSON, SOAP/XML, etc.)

  • Experience working with agile methodology & DevOps frameworks (e.g., Jenkins, Maven, Git) with successful experience working in a collaborative team environment

  • Ability to troubleshoot across layers of the technology stack

  • Ability to leverage his/her experience in delivering and supporting global information systems in an environment for a diverse and distributed user base while relying on a number of enterprise shared services

  • Effective internal and external relationships and operating across functional boundaries

  • Ability to translate strategic opportunities and emerging technology solutions into tangible pragmatic executable plans

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.