Amgen Associate Scientist (Antibody Discovery) in Shanghai, China

Amgen is a leading global biotechnology company with a mission to serve patients around the world. As a science-based, patient-focused organization, we discover and develop innovative therapies to treat serious illnesses. Our medicines have made a dramatic difference in the lives of millions. To underpin our commitment to serve patients in China, Amgen has established a Research and Development facility in Shanghai. Amgen R&D Shanghai Discovery Research laboratory focuses on G protein-coupled receptors (GPCRs), an important class of signaling molecules and potential drug targets. The laboratory is looking for highly self-motivated and creative scientists to join the Antibody Discovery Group. The successful candidates will be integral members of the research team, and work closely with teams in other functional areas and CROs.

Primary responsibilities:

  • Perform antibody library construction and panning/screening for specific mAbs for targets of interest

  • Perform antibody/protein expression and purification and characterization using a wide range of techniques

  • Perform antibody/protein engineering for improved potency and biophysical and pharmacokinetic properties

Basic qualifications

  • Ph.D. in Immunology or Molecular Biology with 0-3 years of related experience, or M.S. in Life Sciences with 3-5 years of related working experience in antibody field.

  • Experience in high throughput screening and biofunction characterization

  • Experience in antibody/protein expression and purification

  • Fluent in reading, writing and speaking English

Preferred qualifications

  • Strong scientific knowledge in antibody engineering and large molecular biophysical property characterization field

  • Proficiency with protein characterization techniques, such as HPLC, FPLC, SEC, etc.

  • Technical expertise in antibody phage display, yeast display, bioassay development

  • Highly self-motivated, creative, and collaborative

  • A proven track record of productivity, effective verbal and written communication and interpersonal skills

Applicants are required to send resumes to meiyunz@amgen.com