Amgen Scientist-Toxicology in Cambridge, Massachusetts

Amgen is seeking a project toxicologist at the Scientist level to work in the

Department of Comparative Biology and Safety Sciences (CBSS) at either our Cambridge, MA, South San Francisco or Thousand Oaks facility. This position will contribute in the drug development process from target identification and validation

through product registration.

Primary responsibilities of the Scientist include:

  • Develop an in-depth understanding and strategy for management of target liabilities.

  • Develop and implement a toxicology strategy for lead optimization and candidate selection.

  • Design and implement a variety of nonclinical investigative and toxicology studies.

  • Manage and analyze a wide range of datasets and literature.

  • Conduct activities related to IND-enabling studies and programs.

  • Work in multi-disciplinary teams with chemists, therapeutic area scientists, pharmacokinetic/drug metabolism experts, and pathologists.

Basic Qualifications:

Doctorate degree


Master's degree and 4 years of Scientific experience


Bachelor's degree and 6 years of Scientific experience

Preferred Qualifications

  • Ph.D. and/or a D.V.M. or M.D.

  • Post-doctoral research experience in a discipline of interest to Amgen (e.g. Neurobiology, Toxicology, Molecular/Cellular biology, Immunology, Endocrinology, Biochemistry, Physiology, or Pathology)

  • 2+ years of academic and/or industry experience in nonclinical drug development demonstrating a sustained record of achievement and the ability to understand translational biology

  • Experience in resolving scientific problems through the establishment of novel protocols to solve experimental questions

  • The ability to critically evaluate and interpret results of scientific experiments and complex, integrated datasets and literature

  • An understanding of cutting-edge science and technology employed to enhance the investigation of drug candidate safety liabilities

  • The ability to work independently, build productive cross-functional collaborations both internally and externally, manage conflict, multi-task, and prioritize work load

  • Demonstrated learning agility, resilience, teamwork skills, and leadership skills

  • Interest and ability to serve as a subject matter expert in a specific discipline

  • Strong understanding of translational biology, the ability to solve problems, and excellent verbal and written communications skills

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.