Amgen Principal Scientist - Toxicologist in Cambridge, Massachusetts
Amgen is seeking a project toxicologist at the Principal Scientist level to work in the Department of Comparative Biology and Safety Sciences (CBSS) at the Cambridge, MA facility. This scientist will contribute in the drug development process from target identification and validation through product registration.
Primary responsibilities of the Principal Scientist include:
Develop in-depth understanding and strategy for management of target liabilities
Develop and implement toxicology strategy for lead optimization and candidate selection
Design and implement nonclinical investigative toxicology studies
Manage and analyze a wide range of datasets and literature
Conduct studies and participate in activities related to the Investigational New Drug (IND) application and market authorization
Work in multi-disciplinary cross-site teams
Take a leading role in developing strong working partnerships with other Amgen Massachusetts (AMA) scientific groups e.g. Translational Systems Biology, Medicinal Chemistry, Neuroscience Research, Pharmacokinetics and Drug Metabolism, Process Development
Doctorate degree & 3 years of scientific experience
Master's degree & 6 years of scientific experience
Bachelor's degree & 8 years of scientific experience
Preferred Qualifications :
Experience in a biological science (e.g. Molecular/Cellular biology, Immunology, Toxicology, Endocrinology, Neurobiology, Biochemistry, Physiology, or Pathology).
Post-doctoral research experience in toxicology, or another specialty discipline (e.g. Molecular/Cellular Biology, Biochemistry or Reproductive/Developmental Biology).
8+ years of academic and/or industry experience in nonclinical drug development demonstrating a sustained record of achievement and the ability to understand translational biology.
Board certification in toxicology.
Excellent verbal and written communications skills.
Experience resolving scientific problems through the establishment of novel protocols.
The ability to critically evaluate, interpret and integrate large datasets and literature.
An understanding of cutting-edge science and technology employed to enhance the investigation of drug candidate safety liabilities.
The ability to work independently, build productive cross-functional collaborations, manage conflict, multi-task, and prioritize.
Demonstrated learning agility, resilience, teamwork skills, and leadership skills.
Interest and ability to serve as a subject matter expert in a specific discipline.
Experience interacting with regulatory agencies.
Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.