Amgen Principal Scientist - Toxicologist in Cambridge, Massachusetts

Amgen is seeking a project toxicologist at the Principal Scientist level to work in the Department of Comparative Biology and Safety Sciences (CBSS) at the Cambridge, MA facility. This scientist will contribute in the drug development process from target identification and validation through product registration.

Primary responsibilities of the Principal Scientist include:

Develop in-depth understanding and strategy for management of target liabilities

Develop and implement toxicology strategy for lead optimization and candidate selection

Design and implement nonclinical investigative toxicology studies

Manage and analyze a wide range of datasets and literature

Conduct studies and participate in activities related to the Investigational New Drug (IND) application and market authorization

Work in multi-disciplinary cross-site teams

Take a leading role in developing strong working partnerships with other Amgen Massachusetts (AMA) scientific groups e.g. Translational Systems Biology, Medicinal Chemistry, Neuroscience Research, Pharmacokinetics and Drug Metabolism, Process Development

Basic Qualifications:

Doctorate degree & 3 years of scientific experience

OR

Master's degree & 6 years of scientific experience

OR

Bachelor's degree & 8 years of scientific experience

Preferred Qualifications :

PhD

Experience in a biological science (e.g. Molecular/Cellular biology, Immunology, Toxicology, Endocrinology, Neurobiology, Biochemistry, Physiology, or Pathology).

Post-doctoral research experience in toxicology, or another specialty discipline (e.g. Molecular/Cellular Biology, Biochemistry or Reproductive/Developmental Biology).

8+ years of academic and/or industry experience in nonclinical drug development demonstrating a sustained record of achievement and the ability to understand translational biology.

Board certification in toxicology.

Excellent verbal and written communications skills.

Experience resolving scientific problems through the establishment of novel protocols.

The ability to critically evaluate, interpret and integrate large datasets and literature.

An understanding of cutting-edge science and technology employed to enhance the investigation of drug candidate safety liabilities.

The ability to work independently, build productive cross-functional collaborations, manage conflict, multi-task, and prioritize.

Demonstrated learning agility, resilience, teamwork skills, and leadership skills.

Interest and ability to serve as a subject matter expert in a specific discipline.

Experience interacting with regulatory agencies.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.